Cardiometabolic diseases
Cardiometabolic diseases such as hardening of the heart, heart attacks and strokes are among the leading causes of death worldwide, often caused by smoking, diabetes and, in particular, obesity (BMI > 30). Obesity is associated with over 200 secondary diseases, including cancer and cardiovascular diseases. Currently, around 1 billion people worldwide are obese, and the trend is rising. Originally developed for diabetes, the GLP1 target could also be important for the treatment of obesity. In addition, there are other receptors such as GIP, glucagen and amylin that could potentially offer even more effective therapeutic approaches, especially for common diseases such as diabetes and obesity.